Coding

Part:BBa_K1963000:Design

Designed by: Frank Sargent   Group: iGEM16_Dundee_Schools   (2016-10-07)


Hfq from E. coli K-12


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

No illegal (RFC[10]) in the natural sequence.


Source

Amplified by PCR from genomic DNA.

References

Cech GM, Szalewska-Pałasz A, Kubiak K, Malabirade A, Grange W, Arluison V, Węgrzyn G. (2016) The Escherichia coli Hfq protein: an unattended DNA-transactions regulator. Front Mol Biosci 3: 36. doi:10.3389/fmolb.2016.00036.

Updegrove TB, Zhang A, Storz G. (2016) Hfq: the flexible RNA matchmaker.Curr Opin Microbiol 30:133-138. doi: 10.1016/j.mib.2016.02.003.

Pfeiffer V, Papenfort K, Lucchini S, Hinton JC, Vogel J. (2009) Coding sequence targeting by MicC RNA reveals bacterial mRNA silencing downstream of translational initiation. Nat Struct Mol Biol 16: 840-846. doi: 10.1038/nsmb.1631.

Chen S, Zhang A, Blyn LB, Storz G. (2004) MicC, a second small-RNA regulator of Omp protein expression in Escherichia coli. J Bacteriol 186: 6689-6697.

Seung Min Yoo, Dokyun Na & Sang Yup Lee (2013) Design and use of synthetic regulatory small RNAs to control gene expression in Escherichia coli. Nature Protocols 8, 1694–1707. doi:10.1038/nprot.2013.105